HIGHLIGHTS
- who: Somsakul Pop Wongpalee et al. from the Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, Mahidol have published the Article: Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a, in the Journal: (JOURNAL)
- what: The authors aimed to apply this CRISPR diagnostic platform to the detection of B. pseudomallei DNA.
- how: By coupling this property of CRISPR-Cas12a or -13a with another signal enhancement step such as metal-enhanced fluorescence (MEF) autocatalysis-driven feedback amplification or an isothermal pre-amplification of nucleic_acids the CRISPR . . .
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