HIGHLIGHTS
SUMMARY
Drugs, targeting to inhibit the activation of the key Hippo pathway effector YAP (Qiao et_al, 2018; Yong et_al, 2021). Recent researches have also proven that the activity of the Hippo pathway is closely related to various anti-tumor immune_responses (Moroishi et_al, 2016), which suggest new and innovative strategies for the development of immunotherapy. Given the critical role of the Hippo signaling pathway in GC growth control and inhibition (Kang et_al, 2016), the authors systematically analyzed the differentially expressed HSPRGs between GC patients and health based on TCGA cohort, and then constructed a prognostic signature . . .
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