Hippocampal glutathione depletion with enhanced iron level in patients with mild cognitive impairment and alzheimer’s disease compared with healthy elderly participants

HIGHLIGHTS

• who: Pravat K. Mandal from the Absolute GSH quantitation The absolute quantitation of in vivo GSH was performed with external calibrated referencing using GSH phantombased in our earlier work, udbffudf12 udbffudf13 TR , exp, AreaGSH, k T Phantom udbffudf12 udbffudf13 u00d7 [Absolute ConcGSH ]=TR m , exp, T GSH . udbffudf12 udbffudf13 TE exp, T Phantom udbffudf12 udbffudf13 u00d7 TE exp, T GSH (1) The relaxation times (, and, ) of GSH, both for phantom and brain tissue were inferred from published literature using T Philips scanner, details of which have been elaborated in our earlier work [10]. Existing literature reports negligible . . .
  

   

  

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