HIGHLIGHTS
- who: Metamorphosis and collaborators from the (UNIVERSITY) have published the article: Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus (Echinodermata: Echinoidea), in the Journal: (JOURNAL)
- what: Specifically, the authors show that; 1) HA acts as a developmental signal leading to precompetent larvae acquiring competence; 2) HA is concentrated in nervous centers implicated in the settlement response in other species; 3) inhibition of H3R or HA synthesis results in spontaneous settlement; and 4) HA has inhibitory effects on caspase mediated arm retraction in metamorphically competent larvae. This study has provided evidence for a modulatory . . .
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