Histamine potentiates sars-cov-2 spike protein entry into endothelial cells

HIGHLIGHTS

  • who: Raghavan S et al. from the Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, United States have published the research work: Histamine Potentiates SARS-CoV-2 Spike Protein Entry Into Endothelial Cells, in the Journal: (JOURNAL)
  • what: The analysis was carried out by semi-quantitative comparison between the surface band intensities compared to the untreated or scrambled siRNA controls and was expressed as the ACE2 surface protein, % untreated control.
  • how: The results showed that ACE2 is predominantly a plasma_membrane (surface)-localized protein in healthy endothelial cells with >85 . . .

     

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