Histone deacetylases function in the control of early hematopoiesis and erythropoiesis

HIGHLIGHTS

  • who: Pascal Vong and colleagues from the Universitu00e9 Picardie Jules Verne, HEMATIM UR4666, Amiens, France have published the article: Histone Deacetylases Function in the Control of Early Hematopoiesis and Erythropoiesis, in the Journal: (JOURNAL)
  • what: HDACs are enzymes capable of deacetylating a wide variety of functional and structural, nuclear and cytoplasmic proteins.
  • how: The hypothesis that reversible histone acetylation may control transcriptional activity was proposed in the 1960s .

SUMMARY

    HDAC6 is the major cytoplasmic deacetylase in humans, and is notably characterized by the presence of two deacetylase domains and . . .

     

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