HIGHLIGHTS
- who: Julien Hardy et al. from the Institut Curie, PSL Research University, UMR3348, Orsay, France, University Paris Sud, Paris-Saclay have published the Article: Histone deposition promotes recombination-dependent replication at arrested forks, in the Journal: (JOURNAL)
- what: The authors propose that restarted forks remain coupled to histone deposition a benefit counterbalanced by the risk to stabilize recombination intermediates detrimental to genome stability. The authors show that H3-H113D precludes (H3-H4)2 tetramer formation, is poorly incorporated into nucleosomes assembled onto DNA and alters the organization of the newly replicated chromatin. The authors provide . . .
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