Histone h3k9 methyltransferase g9a in oocytes is essential for preimplantation development but dispensable for cg methylation protection

HIGHLIGHTS

  • who: Wan Kin Au Yeung from the Medical Institute Kyushu University, Fukuoka, Japan have published the article: Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection, in the Journal: (JOURNAL)
  • what: The authors show H3K9me2-enriched domains mouse oocytes are generally depleted of CG methylation contrasting with their association embryonic stem and somatic cells.
  • how: The results are consistent with the findings reported by Zylicz et_al .

SUMMARY

    G9a (also known as EHMT2) is a mammalian histone methyltransferase that mediates dimethylation of . . .

     

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