Histone methyltransferase setdb1 promotes immune evasion in colorectal cancer via fosb-mediated downregulation of microrna-22 through batf3/pd-l1 pathway

HIGHLIGHTS

• who: Jiale Tian et al. from the Department of Laboratory Medicine, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China have published the research: Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway, in the Journal: Journal of Immunology Research of 20/04/2022
• what: The authors intended to explore the mechanism of histone methyltransferase SETDB1 in immune evasion in CRC. The work demonstrated that SETDB1 could activate the BATF3/PDL1 axis through the inhibition of miR-22 expression and thus promote . . .
  

   

  

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