Hiv-1 infected humanized draga mice develop hiv-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues

HIGHLIGHTS

  • who: Matthew T. Ollerton from the The University of Newcastle, Australia have published the article: HIV-1 infected humanized DRAGA mice develop HIV-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues, in the Journal: (JOURNAL)
  • what: This model has been shown to generate antigen-specific antibodies to various pathogens including influenza A , scrub typhus , and protozoa . In the present study, HIV-infected hDRAGA mice developed modest levels of HIV-specific human IgM and IgG, similar to what was previously seen in hDRAG mice , but lower levels than are typically seen in . . .

     

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