Hiv-1 tat protein promotes neuronal dysfunction through disruption of micrornas*

HIGHLIGHTS

• who: J. Robert Chang from the (UNIVERSITY) have published the paper: HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs*, in the Journal: (JOURNAL) of November/25,/2011
• what: The experiment was performed as suggested by the manufacturer using mice brain tissues (parental and Tat transgenic) or human brain tissues (brain samples from HIV-1-infected patient with encephalitis and normal control brains were obtained from the National NeuroAIDS Tissue Consortium). The authors demonstrated the ability of HIV-1 Tat to cause neuronal deregulation through a miRNAs-dependent pathway. Although the authors demonstrate . . .
  

   

  

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