HIGHLIGHTS
- who: HIV and colleagues from the (UNIVERSITY) have published the paper: HIV integrase and the swan song of the CD4 T cells?, in the Journal: (JOURNAL)
- what: This new study from Cooper et_al proposes an apoptosis molecular mechanism linked to viral integration associated with the activation of p53 and DNA-PK.
SUMMARY
The study also shows that blocking viral integration with raltegravir, an inhibitor of HIV integrase, decreased the occurrence of cell death not only in T/B lymphoblastoid cell line CEMX174, but also in primary CD4 T_cells activated with PHA . . .
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