Hiv protease and integrase empirical substitution models of evolution: protein-specific models outperform generalist models

HIGHLIGHTS

• who: Roberto Del Amparo and Miguel Arenas from the Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain have published the article: HIV Protease and Integrase Empirical Substitution Models of Evolution: Protein-Specific Models Outperform Generalist Models, in the Journal: Genes 2022, 61 of 27/Dec/2021
• what: The authors show that there is a need for protein-specific empirical substitution models of evolution because they can provide accurate likelihood-based phylogenetic inferences, and the authors demonstrate this with the development and evaluation of four new empirical substitution models that mimic the substitution . . .
  

   

  

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