HIGHLIGHTS
- who: Massimiliano Bissa from the National Institutes of Health (Bethesda, MD) and at Bioqual, Inc have published the research: HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC, in the Journal: (JOURNAL) of 11/Dec/2021
- what: The authors report here that the efficacy of DNA/ALVAC/ gp120/alum vaccines based on antibodies mediating apoptosis of infected cells is complemented by efferocytosis a cyclic AMP (cAMP)-dependent antiphlogistic engulfment of apoptotic cells by CD14+ monocytes. Efficacy of DNA/ALVAC/gp120 candidate vaccine is durable in young macaques One . . .
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