Hla dependency and possible clinical relevance of intrathecally synthesized anti-iglon5 igg4 in anti-iglon5 disease

HIGHLIGHTS

• What: The study shows a predominance of IgG4 in 88% of patients.
• Who: Inga Koneczny from the University Hospital Zürich, Switzerland have published the research: HLA dependency and possible clinical relevance of intrathecally synthesized anti-IgLON5 IgG4 in anti-IgLON5 disease, in the Journal: (JOURNAL)
• How: To exactly quantify the IS of anti-IgLON5 IgG4 (zQIgLON5-IgG4) in comparison to total IgG IS (zQTotal IgG) in CSF/serum pairs with available data for QAlb and QIgG and remaining sample volume the authors employed an innovative and sensitive strategy using IS z scores . . .
  

   

  

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