Hlaii peptide presentation of infliximab increases when complexed with tnf

HIGHLIGHTS

• who: Andrea Casasola-LaMacchia from the Seoul National University, South Korea Monash University, Australia have published the Article: HLAII peptide presentation of infliximab increases when complexed with TNF, in the Journal: (JOURNAL)
• what: The work in sought to extend these investigations by using mass spectrometry to detect differences in HLAII presentation of anti-TNF therapeutic-derived peptides in the context of complex formation. The authors examined the effect of antibody-target complex formation on the presentation of therapeutic antibody derived peptides in an ex vivo system which models natural antigen processing and presentation. This investigation . . .
  

   

  

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