HIGHLIGHTS
- who: Giuseppina Divisato from the di Napoli Federico II, Naples, Italy have published the research: Hmga2 protein loss alters nuclear envelope and 3D chromatin structure, in the Journal: (JOURNAL)
- what: The authors observed that, in epiblast stem_cells (EpiSCs), endogenous Hmga2 is mostly associated with heterochromatin regions interacting with Lamins and the authors demonstrated that, in pluripotent stem_cells (PSCs) induced to exit from the nau00efve state, the loss of Hmga2 impacts the deposition and distribution of histone modifications and the integrity of the nuclear envelope.
- how: The authors conducted immunofluorescence experiments to investigate H3K9me2 . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.