HIGHLIGHTS
- What: 2.4.4 Correlation analysis of HMGB2 and immunosuppression gene_expression Correlation analysis was conducted to explore the relationship between HMGB2 and six immunosuppression-related genes, including PDCD1, CTLA4, HAVCR2, TIGIT, LAG3, and CD274 (PD-L1). The study demonstrated that HMGB2 was associated with worse OS, DFS, and PFS in patients, HMGB2 expression was significantly higher in patients with advanced tumor progression or non-response to antitumor therapy.
- Who: Yan-zhu Chen from the Center, United States have published the Article: HMGB2 drives tumor progression and shapes the immunosuppressive microenvironment in hepatocellular carcinoma: insights from . . .
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