Homodimerized cytoplasmic domain of pd-l1 regulates its complex glycosylation in living cells

HIGHLIGHTS

  • who: Li Zhou from the State Key Laboratory Sichuan University, Chengdu, China have published the research work: Homodimerized cytoplasmic domain of PD-L1 regulates its complex glycosylation in living cells, in the Journal: (JOURNAL) of 15/08/2022
  • what: The experiments demonstrated that PD-L1-Y123C and PD-L1Q66BrC7K formed cross-linked homodimers confirming that PD-L1 asymmetrically homodimerized (Fig 3f). The authors demonstrated that membraneanchored full-length PD-L1 forms homodimers in living cells.
  • how: The results indicated that full-length PD-L1 homodimerized in living cells. The results indicated that the . . .

     

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