Homoharringtonine attenuates dextran sulfate sodium-induced colitis by inhibiting nf- κ b signaling

HIGHLIGHTS

  • who: Jiangrui Liu and colleagues from the Department of Gastrointestinal Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, No, Dong Street, Licheng District, Quanzhou, Fujian, China have published the article: Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF- u03ba B Signaling, in the Journal: Mediators of Inflammation of 29/09/2022
  • what: The authors demonstrate the treatment benefit of HHT in DSS-induced colitis and clarify the underlying NF-u03baB signaling mediated proinflammatory cytokines secretion, chemokines expression, macrophage enrichment, and M1 polarization mechanism. This study shows that HHT could suppress macrophage M1 . . .

     

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