Homozygous mutation in dnali1 leads to asthenoteratozoospermia by affecting the inner dynein arms

HIGHLIGHTS

  • who: Yanwei Sha and collaborators from the Nanchang University, China have published the research: Homozygous mutation in DNALI1 leads to asthenoteratozoospermia by affecting the inner dynein arms, in the Journal: (JOURNAL)
  • what: The authors conducted whole-exome sequencing on 126 patients with asthenozoospermia and identified a homozygous mutation in DNALI1 from an infertile patient.
  • how: Routine semen analysis was performed for the patient and the results showed that the patient had normal sperm concentration.

SUMMARY

    More than 80% of male infertility cases exhibit asthenozoospermia, which is caused by the . . .

     

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