Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

HIGHLIGHTS

• who: Marie-Julie Nokin from the (UNIVERSITY) have published the research: Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death, in the Journal: (JOURNAL) of 14/06/2017
• what: The authors demonstrate for the first time the hormetic effect of MG on cancer cell growth and reconcile seemingly contrasting earlier data accumulated on MG. The authors demonstrate for the first time that glycolytic cancer cells are able to induce Nrf2 and GLO1 expression upon MG stress.
• how: The authors evaluated ROS levels in parallel treatment experiments . . .
  

   

  

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