Host genetics and covid-19 severity: increasing the accuracy of latest severity scores by boolean quantum features

HIGHLIGHTS

  • What: The severity scores the authors propose aim at COVID-19 disease, due to its rapid spreading worldwide, has led to the most severe pandemic since the deadly Spanish flu, which killed up to 100 million individuals in the past century. The complexity of COVID-19 immediately suggests that both common and rare variants are expected to contribute to the likelihood of developing a severe form of the disease. Within the GEN-COVID Multicenter Study, about 3,000 patients were sequenced by whole-exome sequencing (WES) and partly (about 2,000) already included in the model described . . .

     

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