HIGHLIGHTS
- who: Feng-Chih Kuo from the Department University of Headington , LE, UK have published the Article: HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution, in the Journal: (JOURNAL) of July/26,/2022
- what: The authors show that the long non-coding RNA HOTAIR (HOX transcript antisense RNA) is exclusively expressed gluteofemoral AT where it is essential for adipocyte development. The authors focused on day 0 (before broad transcript changes associated with impaired adipogenesis were apparent) and looked for overlap with curated gene sets from the Molecular Signatures Database (MSigDB . . .
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