Hotair/mir-1277-5p/zeb1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer

HIGHLIGHTS

• who: Xingyue Weng from the Tumor xenograft experiment All experimental protocols were approved by the Medical Ethics Committee of the First Affiliated Hospital of Zhejiang UniversityThe experimental procedures conformed to the National Institutes of Health Guide for Care and Use of Laboratory Animals (NIH Publications, No., revised, ). First, u00d7 , cells were injected subcutaneously in the lateral flank of, u2010weeku2010old BALB/c nude mice to form tumors. Subsequently, the tumor was sectioned at , mm, and then embedded in subcutaneous tissues. The mice were divided into four groups (n=, mice per group): control, oxaliplatin, NC plus oxaliplatin, shRNA HOTAIR . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.