HIGHLIGHTS
- who: Anna Stein and colleagues from the Department of Hematology, Cell Therapy and Hemostaseology, Leipzig University Hospital, Leipzig, Germany have published the research: How Azanucleosides Affect Myeloid Cell Fate, in the Journal: Cells 2022, 2589 of /2022/
- what: The authors examine the role of DNA methylation in the lineage commitment of stem cells during normal hematopoiesis and consider how mutations in epigenetic regulators such as DNMT3A and TET2 can lead to clonal expansion and subsequent neoplastic progression. The authors aim to provide relevant background information by considering the current understanding of HMA function from a . . .
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