How grail controls treg function to maintain self-tolerance

HIGHLIGHTS

  • who: C. Garrison Fathman from the UCSF, United States Department of Medicine, School of Medicine, Stanford University, Palo Alto, CA, United States have published the research: How GRAIL controls Treg function to maintain self-tolerance, in the Journal: (JOURNAL)
  • what: The authors compared the responses to low dose IL-2 in_vitro, of equal numbers of Tregs isolated from patients with autoimmune diseases or allergic asthma to Tregs from healthy controls, to ask if the defect might be in the number of Tregs. The studies propose a paradigm shift in immune therapy away from immunosuppression to . . .

     

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