How important is the n-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids?

HIGHLIGHTS

• who: Aditya Iyer from the Heinrich Heine University Du00fcsseldorf, Germany have published the article: How important is the N-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids?, in the Journal: (JOURNAL)
• what: The authors aim to give a critical perspective on the impact of N-u03b1-acetylation of u03b1S on its physiological role and pathological aggregation into amyloid fibrils.

SUMMARY

In contrast to Ndats, eukaryotic lysine deacetylases are well-known, and their functions are reviewed elsewhere (Yang and Grégoire, 2007; Choudhary et_al, 2014; Xia et_al, 2020 . . .

 



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