How insulin-like growth factor i binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

HIGHLIGHTS

  • who: Yibin Xu from the G Royal Parade, Parkville, VIC, AustraliaUniversity of have published the research: How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor, in the Journal: (JOURNAL)
  • what: The authors show that the overall conformation of the membrane-distal region of the IGF-I-bound region of the hybrid receptor is closely similar to that seen for IGF-I and IGF-II complexes of the IGF-1R homodimeric receptor (Li et_al, 2019; Xu et_al, 2020).

SUMMARY

    Insulin signaling via . . .

     

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