How to use respiratory chain inhibitors in toxicology studies—whole-cell measurements

HIGHLIGHTS

• who: Mariusz Żuberek and colleagues from the University of Lodz, Lodz, Poland have published the Article: How to Use Respiratory Chain Inhibitors in Toxicology Studies—Whole-Cell Measurements, in the Journal: (JOURNAL) of 27/06/2022
• what: The authors propose a clear experimental setup allowing for complete and credible analysis of redox state of cells under stress conditions which allows for better understanding of effects of ETC inhibition.
• how: The authors used a medium with an elevated glucose concentration (DMEM used in many commercially available media corresponds to acute diabetes shock.

 

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