Hpa axis dysregulation is associated with differential methylation of cpg-sites in related genes

HIGHLIGHTS

  • who: Andreas Chatzittofis from the Medical SchoolUniversity of have published the paper: HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes, in the Journal: Scientific Reports Scientific Reports
  • what: For this study, only the non-fasting blood samples were further studied.
  • how: To avoid overfitting by including too many covariates the authors investigated each individual covariate against the phenotype of interest in multiple linear regression models using the ‘lm' function in R. Covariates were incrementally and independently selected. As there were more than one candidate CpG sites for . . .

     

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