Hsa_circ_0046523 mediates an immunosuppressive tumor microenvironment by regulating mir-148a-3p/pd-l1 axis in pancreatic cancer

HIGHLIGHTS

  • who: Xiaowei Fu from the Department of General Surgery, Affiliated Hospital of Nanchang University, Nanchang, China, Department of have published the paper: Hsa_circ_0046523 Mediates an Immunosuppressive Tumor Microenvironment by Regulating MiR-148a-3p/PD-L1 Axis in Pancreatic Cancer, in the Journal: (JOURNAL)
  • what: The authors focused on the function of miR-148a-3p/PD-L1 molecular axis in_vivo.
  • how: The data were analyzed using FCS Express 6. Flow cytometry results showed that hsa_circ_0046523 knockdown markedly increased the proportion of CD4+ and CD8+ T_cells . The results showed that miR-148a-3p was significantly . . .

     

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