Hsp70-hrd1 axis precludes the oncorepressor potential of n-terminal misfolded blimp-1s in lymphoma cells

HIGHLIGHTS

  • who: Wen-Fang Wang from the Shanghai Institute Tong University University, Shanghai, People's Republic of China have published the article: HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • how: Altogether these results indicated that the metabolism of WT Blimp-1 and a small fraction of each of the mutant Blimp-1 proteins is positively associated with Sumo-2/3 modification in the nucleus. These results indicated that prior association of Blimp-1 mutants with HSP70 may facilitate their recognition . . .

     

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