HIGHLIGHTS
- who: Gen Kuroyanagi and collaborators from the Geriatrics and Gerontology, Japan, Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya have published the research: HSP70 inhibitors upregulate prostaglandin E1-induced synthesis of interleukin-6 in osteoblasts, in the Journal: PLOS ONE of 21/07/2022
- what: The authors investigated whether heat shock protein 70 (HSP70) a molecular chaperone that coordinates protein folding and homeostasis affects PGE1-stimulated IL-6 synthesis in MC3T3-E1 cells through the MAPK activation.
- future: Investigation would be required to elucidate the possible underlying mechanism . . .
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