Hspb8 counteracts tumor activity of braf- and nras-mutant melanoma cells by modulation of ras-prenylation and autophagy

HIGHLIGHTS

• who: Riccardo Cristofani from the Cell culture The human BLM (BRAF-wild-type) melanoma cell line was provided by DrG.N. van Muijen (Department of Pathology, Radbound University Nijmegen Medical Center, Nijmegen, The Netherlands). This cell line is a subline of BRO melanoma cells isolated from lung metastases after subcutaneous inoculation of nude mice with BRO cells [41]. We confirmed the NRASQ R mutation by Sanger sequencing analysis. The human , (BRAFV, mutant) melanoma cell line and , breast cancer cell line were purchased from American Type Culture Collection (ATCC, Manassas, VA, USA). , cell line was authenticated using Short . . .
  

   

  

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