Human airway organoids as 3d in vitro models for a toxicity assessment of emerging inhaled pollutants: tire wear particles

HIGHLIGHTS

  • who: . and collaborators from the University of California, Riverside, United States have published the paper: Human airway organoids as 3D in vitro models for a toxicity assessment of emerging inhaled pollutants: Tire wear particles, in the Journal: (JOURNAL)
  • what: The authors induce primary HBECs to differentiate into hAOs to study the toxicity of TWPs on human airways and evaluate the benefits of hAOs for toxicity studies. The experiments and their aims are summarized in Figure 1. The study reported 3D hAOs derived from HBECs for 14 days of differentiation, and they eventually formed cavity-like . . .

     

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