Human astrocyte spheroids as suitable in vitro screening model to evaluate synthetic cannabinoid mam2201-induced effects on cns

HIGHLIGHTS

  • who: Uliana De Simone and colleagues from the Laboratory of Clinical and Experimental Toxicology, and Pavia Poison Centre-National Toxicology Information Centre, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy have published the research: Human Astrocyte Spheroids as Suitable In Vitro Screening Model to Evaluate Synthetic Cannabinoid MAM2201-Induced Effects on CNS, in the Journal: (JOURNAL) of 11/01/2023
  • what: The study aims to clarify the mechanisms of neurotoxicity induced by one of the most potent SCs named MAM-2201 (a naphthoylindole derivative) by applying a novel three-dimensional (3D) cell culture model . . .

     

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