Human beige adipocytes for drug discovery and cell therapy in metabolic diseases

HIGHLIGHTS

  • who: Amar M. Singh from the Center for Molecular University of of Medicine, Atlanta, GA, USA have published the paper: Human beige adipocytes for drug discovery and cell therapy in metabolic diseases, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • future: Larger-scale studies are needed to understand how beige adipocyte transplantations can be utilized to promote weight loss.

SUMMARY

    Unlike WA, that serve as a storage depot for triglycerides, thermogenic adipocytes oxidize fatty_acids and generate heat through uncoupled mitochondrial respiration, thereby impacting non-shivering thermogenesis. It has been proposed that beige . . .

     

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