Human c1orf27 protein interacts with α2a-adrenergic receptor and regulates its anterograde transport

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  • who: Xin Xu from the Xin Xu and Guangyu Wu* From the Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA Edited by Kirill Martemyanov have published the research work: Human C1orf27 protein interacts with α2A-adrenergic receptor and regulates its anterograde transport, in the Journal: (JOURNAL)
  • what: The authors demonstrate that siRNA-mediated knockdown of C1orf27 markedly impedes the ER-to-Golgi export kinetics of newly synthesized α2A-adrenergic receptor (α2A-AR), a prototypic GPCR, with the half-time being prolonged by more than 65%, in mammalian cells in . . .

     

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