Human dna polymerase ù» functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion dna synthesis*

HIGHLIGHTS

  • who: Giovanni Maga from the (UNIVERSITY) have published the research work: Human DNA Polymerase Ù» Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis*, in the Journal: (JOURNAL) of July/10,/2002
  • what: The authors show that PCNA directly interacts with the newly discovered pol ␭ cloned from human cells. The experiment shown in Fig 1A shows that after 5 min of incubation DNA products longer than 72 nucleotides appeared. To investigate the specific pathway(s) recruiting this enzyme as a first step in understanding its contribution to the maintenance of . . .

     

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