Human foxn1-deficiency is associated with ab double- negative and foxp3 + t-cell expansions that are distinctly modulated upon thymic transplantation

HIGHLIGHTS

• who: Adriana S. Albuquerque and colleagues from the Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisboa, CNRS, UMR, Paris, France have published the research work: Human FOXN1-Deficiency Is Associated with ab Double- Negative and FoxP3 + T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation, in the Journal: (JOURNAL) of May/10,/2012
• what: The aim of this work was to investigate the T-cell compartment of this FOXN1-deficient child and the mechanisms underlying the immunological reconstitution upon thymic transplantation. The . . .
  

   

  

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