Human iapp is contributor to painful diabetic peripheral neuropathy

HIGHLIGHTS

• who: Mohammed M.H. Albariqi and collaborators from the Center for TranslationalUniversity Medical have published the research: Human IAPP is contributor to painful diabetic peripheral neuropathy, in the Journal: (JOURNAL)
• what: The authors provide evidence that hIAPP aggregation is neurotoxic and mediates peripheral neuropathy in mice. Given the accumulating evidence that aggregating hIAPP contributes to development of T2DM , the authors propose that hIAPP Ob/Ob mice are a better model to study T2DM, diabetic neuropathy, and potentially other disease-associated symptoms, as compared with Ob/Ob and db/db mice. The authors found more abundant . . .
  

   

  

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