Human la antigen is required for the hepatitis c virus internal ribosome entry site-mediated translation*

HIGHLIGHTS

  • who: Naushad Ali from the (UNIVERSITY) have published the article: Human La Antigen Is Required for the Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation*, in the Journal: (JOURNAL) of February/22,/2000
  • what: The authors have demonstrated novel features of the La-HCV IRES interaction and their functional consequences during the IRES-controlled translation. The authors demonstrate that the mutant protein representing C-terminal half of La antigen (La 229 - 408) also binds the 5⬘-NCR efficiently and modestly stimulates the HCV IRES-directed translation in RRL.
  • how: Because La 229 . . .

     

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