Human leukocyte antigen evolutionary divergence as a novel risk factor for donor selection in acute lymphoblastic leukemia patients undergoing haploidentical hematopoietic stem cell transplantation

HIGHLIGHTS

• What: The authors scored HED for donors, recipients, and donor-recipient pairs, and assessed the clinical significance of class I and II HED in 225 ALL patients who received HLA-haploidentical HSCT from a related donor. The aim was to assess the impact of HED on relapse, non-relapse mortality (NRM), and acute and chronic graftversus-host disease (GVHD). The authors report the impact of HED scores on clinical outcomes for ALL patients underwent haploidentical HSCT.
• Who: Rémy Dulery and colleagues from the Hôpital Saint-Antoine, France Essen University Hospital, Germany have published . . .
  

   

  

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