Human leukocyte antigen super-locus: nexus of genomic supergenes, snps, indels, transcripts, and haplotypes

HIGHLIGHTS

  • who: Jerzy K. Kulski from the (UNIVERSITY) have published the article: Human leukocyte antigen super-locus: nexus of genomic supergenes, SNPs, indels, transcripts, and haplotypes, in the Journal: (JOURNAL) of 21/Dec/2022

SUMMARY

    The human Major Histocompatibility Complex (MHC) on the short arm of chromosome 6 (band p21.3) is a Human Leukocyte Antigen (HLA) super-locus composed of clusters of many tightly linked supergenes involved with various phenotypic functions, mostly in connection with the immune_response1-4. Reliable MHC linkage mapping and haplotyping usually are dependent on pedigree studies of particular genotyped . . .

     

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