Human mesenchymal stem cells improve rat islet functionality under cytokine stress with combined upregulation of heme oxygenase-1 and ferritin

HIGHLIGHTS

  • who: Camille Laporte from the Laboratory of Fundamental and Applied Bioenergetics (LBFA), INSERM U , and SFR Environmental and Systems Biology (BEeSy), University Grenoble Alpes, Grenoble, BP, Grenoble , France have published the paper: Human mesenchymal stem cells improve rat islet functionality under cytokine stress with combined upregulation of heme oxygenase-1 and ferritin, in the Journal: (JOURNAL)
  • what: The authors showed that the loss of insulin secretion induced by exposure to cytokines was partially prevented by MSC co-culture. The authors demonstrated that MSCs induced preservation of HO-1 and ferritin H protein levels in islets . . .

     

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