Human metapneumovirus m2-2 protein inhibits rig-i signaling by preventing trim25-mediated rig-i ubiquitination

HIGHLIGHTS

• who: Yukie Tanaka from the United States Monash University, Australia have published the paper: Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination, in the Journal: (JOURNAL)
• what: The authors focused on the mechanism(s) underlying RIG-I inhibition by M2-2. This study has revealed that the mechanism underlying HMPV-M2-2 protein-mediated innate immune inhibition is similar to that by V proteins of several members of the family Paramyxoviridae .
• how: These results indicated that M2-2 inhibits RIG-I/TRIM25 signaling and suppresses . . .
  

   

  

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