Human microglia extensively reconstitute in humanized-blt mice with human interleukin-34 transgene and support hiv-1 brain infection

HIGHLIGHTS

• who: Jianshui Zhang from the Universitu00e9 Claude Bernard Lyon, France University of North Carolina at have published the paper: Human Microglia Extensively Reconstitute in Humanized-BLT Mice With Human Interleukin-34 Transgene and Support HIV-1 Brain Infection, in the Journal: (JOURNAL)
• what: This study has been poised to address two questions using the hu-BLT hIL34-Tg NOG (hu-BLT-hIL34) mouse model. The authors demonstrated that human microglia can be extensively reconstituted in CNS from circulating human HSPCs in hu-BLT-hIL34 mice.
• how: All above antibodies and isotype control METHOD . . .
  

   

  

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