HIGHLIGHTS
- who: Maria Teresa Pagano and colleagues from the Center for Gender Specific Medicine, Istituto Superiore di Sanitu00e0, Rome, Italy have published the paper: Human Monocyte-Derived Dendritic Cells Are the Pharmacological Target of the Immunosuppressant Flavonoid Silibinin, in the Journal: (JOURNAL)
- what: The authors have attempted to ascertain whether Silibinin influences the maturation cytokine production and antigen-presenting capacity of human monocyte-derived DC. The authors show that Silibinin significantly suppresses the upregulation of costimulatory and MHC molecules in LPS-stimulated mature DC and inhibits lipopolysaccharide (LPS)-induced interleukin (IL)-12 IL-23 and TNF . . .
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