Human multipotent mesenchymal stromal cells cytokine priming promotes rab27b-regulated secretion of small extracellular vesicles with immunomodulatory cargo

HIGHLIGHTS

• who: Anastasia Cheng from the Research Institute of the McGill University Health Centre, McGill University, Decarie Blvd, Office # EM2-3238, Montreal, QC H A , Canada have published the research work: Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo, in the Journal: (JOURNAL)
• what: The authors provide a detailed proteomic analysis of cytokineinduced sEVs enriched in small exosome-like EVs from human AT-MSCs. The authors demonstrate that the proteomic cargo of AT-MSC-sEVs shifts in response to proinflammatory cytokines. The study shows that primed . . .
  

   

  

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